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. 2002 Jun;128(3):516–524. doi: 10.1046/j.1365-2249.2002.01858.x

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© 2002 Blackwell Science Ltd

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Fig. 3 — IL-12 production in PBMC from patients with MDRTB in response to the PPD antigen of M. tuberculosis. IL-12 p40 and p70 production in PBMC were determined after in vitro stimulation with PPD antigen. Supernatant fluids were prepared after 18 h and cytokine concentrations were measured using ELISA. Values are the mean ± s.d. of triplicate supernatant samples. (a) IL-12 p40 production in MDRTB patients. (b) IL-12 p70 production in MDRTB patients. A significant correlation was found between (c) IL-12 p40 and IL-10 (n = 18, r = 0·94, P < 0·001), whereas no significant correlation was found between (d) IFN-γ and IL-12 p40 production in TB patients (n = 18, r = 0·24, P > 0·05).