Table 3.
Characteristics of patients with highly severe forms of vasculitis due to hepatitis C-associated mixed cryoglobulinemia
| Patients, sex, age | ASAT IU/1 | ALAT IU/l | HCV RNA | Knodell index | Cryo type | Clinical symptoms |
|---|---|---|---|---|---|---|
| 1. M, 61 | 11 | 20 | + | 5 | III | S, J, DT, PN, K |
| 2. M, 63 | 34 | 17 | + | 11 | II | S, J, K (MPGN) |
| IgMκ | ||||||
| 3. F, 36 | 21 | 16 | + | 2 | II | S, PN, CNS, K |
| IgMκ | ||||||
| 4. M, 60 | 9 | 50 | + | 7 | II | S, J, PN, GS |
| IgMκ | ||||||
| 5. F, 72 | 60 | 75 | + | ND | II | S, J, K (MPGN) |
| IgMκ | ||||||
| 6. M, 71 | 90 | 120 | + | 6 | II | S, J, PN, GS |
| IgMλ | ||||||
| 7. F, 81 | 24 | 32 | + | 6 | II | S, PN, GS |
| IgMκ | ||||||
| 8. M, 58 | 73 | 60 | + | 8 | II | S, PN |
| IgMλ | ||||||
| 9. F, 66 | 77 | 62 | + | 6 | II | S, J, PN |
| IgMκ | ||||||
| 10. F, 74 | 70 | 40 | + | 10 | II | S, J, PN |
| IgMκ | ||||||
| 11. F, 59 | 52 | 65 | + | 7 | III | S, PN |
| 12. M, 81 | 30 | 41 | + | ND | II | S, PN, CNS |
| IgMκ | ||||||
| 13. F, 70 | 100 | 120 | + | ND | II | S, PN, GS |
| IgMκ | ||||||
| 14. M, 71 | 22 | 40 | + | 5 | II | S, DT, K (MPGN) |
| IgMκ | ||||||
| 15. F, 62 | 68 | 85 | + | 10 | II | S, J, PN |
| IgMκ | ||||||
| 16. M, 72 | 28 | 35 | + | 5 | III | S, PN, GS |
| 17. F, 54 | 200 | 300 | + | 11 | II | S, PN |
| IgMκ | ||||||
| 18. F, 76 | 40 | 46 | + | 5 | II | S, J, PN |
| IgMκ |
S: skin, J: joints, DT: digestive tract, K: kidney, MPGN: mem-branoproliferative glomerulonephritis, PN: peripheral nerve, CNS: central nervous system, GS: general symptoms (fever, weight loss).