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. 1998 Feb 17;95(4):1500–1504. doi: 10.1073/pnas.95.4.1500

Figure 4.

Figure 4

Sequence comparison of the 1.7-kb segment from the human 9-kb fragment with the mouse PAH gene enhancer. Similarity between the 1.7-kb segment from the human 9-kb fragment and the mouse PAH gene enhancer was analyzed by the program bestfit, Wisconsin Package Version 9.0, Genetics Computer Group (GCG). The first base of the second XbaI site (see Fig. 3) in the 9-kb fragment was numbered 1. The HNF1 binding sites defined in the mouse PAH gene enhancer and the human homologous sequences are boxed. The mouse sequences in the boxes correspond to the HNF1 footprint regions (23).