Table 2.

Release of IL-4 and IFN-γ from lung cells. Lungs were enzymatically-digested and cells stimulated for 6 h with anti-CD3. The concentration of cytokines was determined by ELISA. The IL-4 levels decreased significantly in re-infected BALB/c mice compared with non-infected BALB/c mice (P < 0·05). The IFN-γ levels were significantly increased in singly- and re-infected mice compared with non-infected mice(P < 0·01). Medians are presented with the range in parenthesis

	Non-infected median (range)	Singly-infected median (range)	Re-infected median (range)
IL-4	42 (25–56 pg/ml)	39 (25–88 pg/ml)	23·5 (0–40 pg/ml)*
IFN-γ	23 (0–90 pg/ml)	350 (230–690 pg/ml)†	465 (140–1110 pg/ml)†

^*Significantly lower compared with non- or singly-infected mice (P < 0·05).

^†Significantly higher compared with non-infected mice (P < 0·01).