Table 1.

Median (range) sCD14 serum levels (ng/ml) in Helicobacter pylori⁺ and H. pylori⁻ subjects and in different –159C/T genotypes

	n	All genotypes median (range)	n	CC-genotype median (range)	n	CT and TT genotypes median (range)	CC versus CT/TT †
Combined group (groups 1 and 2)
All subjects	328	1315 (714–2620)	146	1240 (714–2620)	182	1400 (814–2600)	P < 0·001
H. pylori+	161	1400 (855–2620)	72	1300 (855–2620)	89	1420 (890–2600)	P=0·016
H. pylori−	167	1280 (714–2000)	74	1190 (714–2000)	93	1350 (814–1970)	P < 0·001
Hp−versus Hp+*		P < 0·001		P=0·002		P=0·025
Group 1 (dyspeptic patients)
All subjects	201	1400 (875–2620)	91	1260 (875–2620)	110	1430 (890–2600)	P < 0·001
H. pylori+	117	1410 (875–2620)	52	1310 (875–2620)	65	1440 (890–2600)	P = 0·015
H. pylori−	84	1300 (909–2000)	39	1200 (909–2000)	45	1400 (960–1970)	P = 0·001
Hp−versus Hp+*		P = 0·013		P = 0·019		P = ns
Group 2 (control subjects)
All subjects	127	1270 (714–2010)	55	1210 (714–1890)	72	1300 (814–2010)	P = 0·018
H. pylori+	44	1300 (855–2010)	20	1290 (855–1890)	24	1300 (112–0 2010)	P = ns
H. pylori−	83	1240 (714–1850)	35	1140 (714–1700)	48	1300 (814–1850)	P = 0·015
Hp−versus Hp+*		P = 0·05		P = 0·08		P = ns

^*Comparison between H. pylori⁺ subjects and H. pylori⁻ subjects within each genotype (Mann–Whitney U-test).

^†Comparison between subjects with CC genotype versus CT or TT genotypes (Mann–Whitney U-test).