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. 2002 Jul;129(1):43–53. doi: 10.1046/j.1365-2249.2002.01875.x

Fig. 2.

Fig. 2

Fig. 2

Fig. 2

Urinary protein excretion over 24h measured on days 1, 4, 8, 11 and 14 after the injection of NTS. (a) Saline (•), anti-P-selectin monoclonal antibody (mAb) (ARP 2–4)(□), mouse IgG (▪) and normal control (○) group. Urinary protein excretion in saline group significantly increases after day 8, compared with normal control group. Administration of ARP 2–4 decreases urinary protein excretion on day 14 compared with mouse IgG group. Data are mean ± SEM of 8 rats in each group. *P < 0·01 versus mouse IgG group, ** P < 0·01 versus saline group. (b) Anti-L-selectin mAb (HRL3; ○) and non-neutralizing anti-L-selectin mAb (HRL2; •) group. There is no difference in urinary protein excretion between the groups. (c) Sulphated colominic acid (SCA: 5mg/kg/day; • and 10mg/kg/day; ○) and nonsulphated colominic acid CA (10mg/kg/day; □) group. Urinary protein excretion significantly decreases in SCA group after day 8, compared with CA group, in a dose-dependent manner. Data are mean ± SEM of 8 rats in each group. *P < 0·01 versus CA group, ** P < 0·01 versus SCA (5mg/kg/day) group.