Histopathological findings of the kidney in crescentic glomerulonephritis in WKY rats on day 14. (a) Normal control group, (b) Saline group, (c) CA group, (d) SCA (10mg/kg/day) group (PAS staining, scale bar = 100μm). Note severe mesangial hypercellularity, mesangial matrix expansion, necrotizing lesions and cellular crescent formation are observed in the kidneys of saline and CA groups. In comparison, note the improvement in histopathological changes in the SCA group.