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Decrease in the expansion of NKT cells in the liver of NKT-deficient mice induced by the injection of denatured liver tissue
| % Fluorescence-positive cells | |||
|---|---|---|---|
| Mice | Injection of denatured liver tissue | NK1·1+ CD3int | NK1·1+ CD4+ |
| B6 | – | 18·5 ± 4·3 | 16·2 ± 3·6 |
| day 1 | 44·8 ± 11·0* | 34·1 ± 9·8* | |
| TAP-1 (–*–) | – | 11·4 ± 1·2 | 8·7 ± 0·9 |
| day 1 | 25·3 ± 4·6 | 16·7 ± 8·5 | |
| CD1d (–/–) | – | 2·8 ± 0·2 | 0·3 ± 0·1 |
| day 1 | 12·8 ± 4·4* | 1·7 ± 0·2 | |
| β2m (−/−) | – | 2·2 ± 0·1 | 0·6 ± 0·1 |
| day 1 | 11·9 ± 3·3* | 0·7 ± 0·1 | |
P < 0·05, n = 4.
