Fig. 5.

Ultrastructure of mitochondria in 3h cereulide-treated NK cells (a, NK-92; c, e, fresh NK cells) and controls (b, NK-92; d, f, fresh NK cells). Samples were treated with/without 1000 ng/ml cereulide, followed by cryofixation and freeze-substitution. Swollen mitochondria with moderately stained matrix and translocated cristae after toxin-treatment (a, c, e) versus intact mitochondria with an intensely stained matrix and regularly arranged cristae in control cells (b, d and f); scale bars = 1μm.