Table 2.
Cytokine produccion by T cells of the patients
| Percentage of positive T cells | ||
|---|---|---|
| Patients† | IL-4 | IFN-γ |
| DM 1 | 2·12 | 6·21 |
| (0·71–5·19) | (1·75–13·8) | |
| APS | 3·77 | 13·42 |
| (0·8–8·5) | (7·1–20·81) | |
| SMS | 4·88 | 9·22 |
| (0·67–9·8) | (3·7–18·3) | |
| CAPA | 4·73 | 27·06* |
| (0·84–14) | (14·73–43·12) | |
| Control A | 1·03 | 12·04 |
| (0·22–1·8) | (2·83–21·65) | |
| Control B | 1·3 | 2·05 |
| (0·75–1·71) | (0·31–3·94) | |
The results are expressed as average and (range) number of CD3+ cytokine+ cells after 3 day stimulation with GAD.
*
P < 0·005.
†
DM 1, type 1 diabetes mellitus; APS, autoimmune type 2 polyendocrine syndrome; SMS, stiff-man syndrome; CAPA, cerebellar ataxia associated with polyendocrine autoimmunity; Control A, control donors with 20 years average age; Control B, control donors with 57 years average age.