Table 1.

Binding of serum antibodies to N- and C-terminal peptides of GAD

Patient group	Binding to N-term. Peptides: no. of + ve (no. of tested)	Binding to C-term. Peptides: no. of + ve (no. of tested)
SMS	1a (3b)	1a (4b)
APS II (non-DM)	4 (19)	1c (6)
APS II (DM)	2 (12)	n.d.d

^aThe same non-diabetic SMS patient (DH) was positive for antibodies to N- and C-terminal peptides.

^bOne of the SMS patients (LB) was diabetic.

^cThis non-diabetic APS II patient, who was positive for antibodies to the C-terminal peptide, was not positive for antibodies to the N-terminal peptide.

^dNot done.