Table 2.
Clinical disease in glomerulonephritis model
| WT | C5aRKO | |||
|---|---|---|---|---|
| 3 week | 6 week | 3 week | 6 week | |
| Hematuria (0–5+) (mean (SD)) | 0.0 (0) | 3·5 (1.6) | 0·2 (0·4) | 2·3 (1.8) |
| Proteinuria (0–4+) (mean (SD)) | 2·3 (0·6) | 3·0 (0) | 2·0 (0·6) | 3·7 (0·5) |
| BUN (mean (SD)) | 27·0 (0) | 45·3 (17.6) | 19·3 (1.8)* | 33·5 (9.2) |
P < 0·001 compared to wild type at the same time.