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The glycolysis inhibitor 2-DG induces apoptosis in c-Myc-overexpressing cells. (A) Rat fibroblasts exposed to 10 mM 2-DG for 1 day were harvested for flow cytometric analysis of apoptosis. (B) Various lymphoid cells were exposed to 10 mM 2-DG for 1 day before they were fixed for analysis of apoptosis. (C) Human small cell lung cancer cells were treated with 10 mM 2-DG for 1 day before subjected to the apoptosis assay.
