Fig. 3.

Significant correlations (that we interpret as genetic overlap) among three neurodevelopmental disorders (autism, bipolar disorder, and schizophrenia; corresponding nodes are shown in yellow) and all other disorders in our data set (blue nodes). The volume of each sphere (disease) is proportional to the number of patient records annotated with the corresponding phenotype, as explained in the key. The arcs represent significant correlations among phenotypes, with negative correlations shown in blue and positive correlations shown in red. Thicker arcs represent stronger correlations; see key.