Fig. 6.

Analysis of microarray chips showing heatmap of gene expression and cluster analysis. (a) Modulation of the endothelial cell transcriptome following co-culture with Plasmodium falciparum strain ItG-infected and uninfected red blood cells (PRBC and RBC, respectively) in the absence and presence of 5 pg/ml TNF for 6 h, analysed using Affymetrix human genome chip and ArrayMiner software, showing seven non-hierarchical clusters with a total of 8105 genes, having a P value less than 0.001. (b) Three out of the seven clusters showing differential significant changes in gene expression. The data were taken from four separate experiments.