Table 4.
RT-PCR Findings in Bone Marrow Samples Infiltrated by Different Childhood Tumors including RMS, Acute Lymphatic Leukemia, Neuroblastoma, and Ewing’s Sarcoma
| Cases | PAX3/FKHR | α/γAChR | Myogenin | MyoD1 |
|---|---|---|---|---|
| Bone Marrow | 0 /26 | 0 /26* | 4 /26 | 0 /26 |
| BM/RMS (n = 5) | 5 /5 | 5 /5† | 5 /5 | 0 /5 |
| BM/ALL (n = 4) | 0 /4 | 0 /4* | 2 /2 | 0 /4 |
| BM/NB (n = 8) | 0 /8 | 0 /8* | 2 /4 | 0 /8 |
| BM/Ewing’s (n = 4) | 0 /4 | 0 /4* | 2 /4 | 0 /4 |
Bone marrow was from alveolar RMS patients, free of alveolar RMS, confirmed by Pax3/FKHR RT-PCR.
BM/RMS, bone marrow infiltrated by alveolar RMS; BM/ALL, bone marrow infiltrated by acute lymphatic leukemia; BM/NB: bone marrow infiltrated by neuroblastoma; BM/Ewing’s: bone marrow infiltrated by Ewing’s sarcoma.
α/γAChR ratio ≫1
α/γAChR ratio <1