Table 5.
Selected Readings: Molecular Oncology (Solid Tumors)
| Barr FG, Chatten J, D’Cruz CM, Wilson AE, Nauta LE, Nycuym LM, Biegel JA, Womer RB: Molecular assays for chromosomal translocations in the diagnosis of pediatric soft tissue sarcomas. J Am Med Assoc 1995, 273:553–557 |
| Barr FG: Translocations, cancer and the puzzle of specificity. Nature Genet 1998, 19:121–124 |
| Blackwood MA, Weber BL: BRCA1 and BRCA2: From molecular genetics to clinical medicine. J Clin Oncol 1998, 16:1969–1977 |
| Brodeur G, Seeger R, Sather H, Dalton A, Siegel S, Wong K, Hammond D: Clinical implications of oncogene activation in human neuroblastomas. Cancer 1986, 58:541–545 |
| Castilla LH, Couch FJ, Erdos MR, Hoskins KF, Calzone K, Garber JE, Boyd J, Lubin MB, Deshano ML, Brody LC, Collins FS, Weber BL: Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer. Nature Genet 1994, 8:387–391 |
| Evan G, Littlewood T: A matter of life and cell death. Science 1998, 281:1317–1322 |
| Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990, 61:759–767 |
| Fearon ER: Human cancer syndromes: Clues to the origin and nature of cancer. Science 1997, 278:1043–1050 |
| Ford D, Easton DF, Stratton M, Narod S, Goldgar D, Deville P, Bishop DT, Weber B, Lenoir G, Chang-Claude J, Sobol H, Teare MD, Struewing J, Arason A, Scherneck S, Peto J, Rebbeck TR, Tonin P, Neuhausen S, Barkardottir R, Eyfjord J, Lynch H, Ponder BA, Gayther SA, Zelada-Hedman M, et al: Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. Am J Hum Genet 1998, 62:676–689 |
| Harris CC, Hollstein M: Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993, 329:1318–1327 |
| Hibshoosh H, Lattes R: Immunohistochemical and molecular genetic approaches to soft tissue tumor diagnosis: A primer. Semin Oncol 1997, 24:515–525 |
| Ionov Y, Peinado MA, Malkhosyan MS, Shibata D, Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993, 363:558–561 |
| Kinzler K, Vogelstein B: Lessons from hereditary colon cancer. Cell 1996, 87:159–170 |
| Ladanyi M: The emerging molecular genetics of sarcoma translocations. Diagn Mol Pathol 1995, 4:162–173 |
| Liu B, Nicolaides NC, Markowitz S, Willson JK, Parsons RE, Jen J, Papadopolous N, Peltomaki P, de la Chapelle A, Hamilton SR, Kinzler KW, Vogelstein B: Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nature Genet 1995, 9:48–55 |
| Malkin D, Li FP, Strong LC, Fraumeni JF Jr, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA: Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990, 250:1233–1238 |
| Menke A, McInnes L, Hastie ND, Schedl A: The Wilms’ tumor suppressor WT1: approaches to gene function. Kidney Int 1998, 53:1512–1518 |
| Mulligan G, Jacks T: The retinoblastoma gene family: cousins with overlapping interests. Trends Genet 1998, 14:223–229 |
| Newman B, Mu H, Butler LM, Millikan RC, Moorman PG, King M-C: Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. J Am Med Assoc 1998, 279:915–921 |
| Persons DL, Borelli KA, Hsu PH: Quantitation of HER-2/neu and c-myc gene amplification in breast carcinoma using fluorescence in situ hybridization. Mod Pathol 1998, 10:720–727 |
| Philipson L: Cell cycle exit: growth arrest, apoptosis, and tumor suppression revisited. Mol Med 1998, 4:205–213 |
| Ponder B: Genetic testing for cancer risk. Science 1997, 278:1050–1054 |
| Powell SM, Petersen GM, Krush AJ, Booker S, Jen J, Giardiello FM, Hamilton SR, Vogelstein B, Kinzler KW: Molecular diagnosis of familial adenomatous polyposis. N Engl J Med 1993, 329:1982–1987 |
| Schwab M: Amplification of oncogenes in human cancer cells. Bioessays 1998, 20:473–479 |
| Sidransky D: Nucleic acid-based methods for the detection of cancer. Science 1997, 278:1054–1059 |
| Singleton TP, Strickler JG: Clinical and pathologic significance of the c-erbB-2 (HER-2/neu) oncogene. Pathol Annu 1992, 27 (Part 1): 165–190 |
| Staunton MJ, Gaffney EF: Apoptosis: basic concepts and potential significance in human cancer. Arch Pathol Lab Med, 1998, 122:310–319 |
| Thibodeau SN, Bren G, Schaid D: Microsatellite instability in cancer of the proximal colon. Science 1993, 260:816–819 |
| Willman CL, Busque L, Griffith BB, Favara BE, McClain KL, Duncan MH, Gilliland DG: Langerhans’-cell histiocytosis (histiocytosis X)—a clonal proliferative disease. N Engl J Med 1994, 331:154–160 |