Table 1.
Summary of Results
| Histologic group | CHOP | TLS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Overall result | Results by restriction digest | Overall result | Results by restriction digest | |||||||
| BamHI and SacI digests* | BamHI | SacI | HindIII | EcoRI | BclI | BamHI | PstI | |||
| Myxoid LS (n = 42) | 42 R | 35 R | 38 R | 38 R | 1 R | 1 R | 38/42 R | 32 R | 3 R | 1 R |
| 2 G | 3 G | 5 G | ||||||||
| 2 F | 1 F | 2 F | ||||||||
| Predominantly myxoid WDLS (n = 17) | 17 G | 17 G | 17 G | 17 G | 6 G | 3 G | 12 G | 10 G | 2 G | 2 G |
| WDLS with minor or no myxoid areas (n = 17) | 17 G | 14 G | 17 G | 14 G | 8 G | 4 G | 9 G | 2 G | 6 G | 2 G |
| 1 F | ||||||||||
| Pleomorphic LS (n = 3) | 3 G | 3 G | 3 G | 3 G | 2 G | ND | 1 G | 1 G | ND | ND |
| Myxofibrosarcoma (n = 13) | 13 G | 12 G | 13 G | 12 G | 7 G | 4 G | 5 G | 4 G | ND | 1 G |
LS, liposarcoma; WDLS, well-differentiated LS; R, rearranged; G, germline; F, failure; ND, not done.
Except for this column, which shows the number of cases with identical results for both enzymes, in cells where the number of cases is less than n, the remaining cases were not studied with the enzyme in question, unless otherwise specified.
Includes 2 cases that showed TLS rearrangement in EcoRI digests only; for details on 4 cases without detectable TLS rearrangement, see Results.