Table 3.

Sensitivity of Individual Probes and Complementation Analysis for Urothelial Carcinoma Detection

Dark shaded cells indicate cases positive for malignancy with the CEP7 probe; grey shaded cells indicate cases negative for malignancy with the CEP7 probe but positive with other probes (ie, CEP3, CEP7, or LSI 9p21).

TNM tumor stage based on biopsy or surgical resection.

The cutoff for abnormal percentage of cells with tetrasomy is indicated below each probe except LSI 9p21.

The cutoff for abnormal percentage of cells with homozygous deletion indicated below probe LSI 9p21.

Positive cytology (grade 3 TCC) but no biopsy. However, imaging studies reveal an obvious renal pelvic tumor.

Suspicious cytology (atypical cells suspicious for carcinoma) and previous pTa tumor.

Negative cytology and biopsy, but previous biopsy revealed a grade 2 pTa tumor.

ND, not determined.