Table 3.
Sensitivity, Specificity, and Predictive Value of Quantitative CMV Viral Burden Analysis
| Virus | True positive* | False positive | False negative | True negative | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|---|---|
| Qualitative CMV | 8 | 26 | 0 | 230 | 100% | 90% | 24% | 100% |
| Quantitative CMV at 10,000 VT/ml cutoff | 8 | 0 | 0 | 256 | 100% | 100% | 100% | 100% |
A sample was considered to be a true positive for a CMV-related disease if it gave a positive result or a value above the cutoff and was harvested within 5 weeks of evidence of CMV etiology by histology, serology, and/or non-immune-mediated tissue destruction.