Table 2.
Genes Expressed at Higher Levels in the Neuroblastoma Cell Line
| Ratio* | Map | Gene | IMAGE no. | Ratio | Map | Gene | IMAGE no. |
|---|---|---|---|---|---|---|---|
| 9.06 | 10p15 | GATA3 | 214068 | 2.54 | 11q13 | CCND1 | 841641 |
| 7.39 | 5q | ISL1 | 362795 | 2.52 | Unknown | EST | 503064 |
| 7.19 | 2p24.1 | MYCN | 298309 | 2.50 | 4q11–q12 | KIT | 265060 |
| 6.68 | 2p25 | ODC1 | 545502 | 2.48 | 7q11.23 | GTF2IP1 | 548957 |
| 6.48 | 6q21 | CD24 | 204335 | 2.47 | 1 | CELSR2 | 175103 |
| 6.20 | 6p21.3 | HSPA1A | 265267 | 2.47 | 20p13 | CENPB | 809720 |
| 5.59 | 17 | EST | 430186 | 2.47 | 18 | EST | 364506 |
| 5.54 | 10 | INA | 784876 | 2.45 | Xp22.2–p22.1 | PDHA1 | 489212 |
| 5.38 | 6p21.3 | HSPA1A | 265267 | 2.43 | 3q27–q28 | SIAT1 | 194295 |
| 5.23 | 6q21 | CD24 | 163189 | 2.37 | 6p21.3 | ZNF184 | 814014 |
| 5.08 | 20q13.3 | KCNQ2 | 179534 | 2.35 | 5q21–q23 | CAMK4 | 814780 |
| 4.55 | 16p13.2 | EMP2 | 109863 | 2.34 | 8 | KIAA1249 | 291537 |
| 4.40 | 2 | IGFBP5 | 45542 | 2.33 | 10q26 | OAT | 783696 |
| 4.34 | 3p21.3 | MST1R | 612616 | 2.33 | 20pter–p12 | PCNA | 789182 |
| 3.98 | Unknown | EST | 530662 | 2.32 | 5 | PPIC | 487437 |
| 3.90 | 1 | RGS4 | 429349 | 2.30 | 7q22 | TRIP6 | 811108 |
| 3.85 | 12q13 | KRT8 | 897781 | 2.30 | 14q32.32 | AKT1 | 785669 |
| 3.64 | 1p22 | D1S155E | 839623 | 2.25 | 11q13 | UCP2 | 236034 |
| 3.62 | 6p22.3 | SOX4 | 366815 | 2.20 | 2q31 | COL3A1 | 122159 |
| 3.56 | 4q34–q35 | FACL2 | 82734 | 2.20 | 16q22 | ATP6D | 384078 |
| 3.55 | 2p25 | ODC1 | 796646 | 2.19 | 17p13.2–p13.3 | MYO1B | 840474 |
| 3.52 | 19 | EIF3S4 | 857319 | 2.17 | 9q22 | C9ORF3 | 768292 |
| 3.36 | 20q12 | NCOA3 | 502333 | 2.15 | 12p13 | CD9 | 727251 |
| 3.32 | 2 | EST | 768324 | 2.14 | 16q13–16q21 | MMP15 | 784589 |
| 3.22 | 22q12.3 | TIMP3 | 75410 | 2.14 | 11 | IFITM1 | 509641 |
| 3.19 | 3q13.1–q13.2 | GAP43 | 44563 | 2.10 | 17q | CBX1 | 786084 |
| 3.17 | 20p13 | CDC25B | 786067 | 2.09 | Xq26 | FHL1 | 813266 |
| 3.10 | 6q27 | PDCD2 | 303183 | 2.08 | 18 | EST | 141234 |
| 2.97 | 6p21.3 | HSPA1L | 50615 | 2.08 | 3q12–q13 | MOX2 | 51363 |
| 2.89 | Xp11.4–p11.3 | MAOA | 359661 | 2.08 | 16p13.3 | SRM300 | 489453 |
| 2.82 | 19p13.1 | IFI30 | 724506 | 2.07 | 1q31–q32 | PTPRC | 239287 |
| 2.80 | 18q21.3 | BCL2 | 342181 | 2.04 | Xq11 | TM4SF2 | 307471 |
| 2.79 | 7q22 | CUTL1 | 701751 | 2.02 | 20q11.2–q12 | NNAT | 139681 |
| 2.78 | 20p13 | CDC25B | 786067 | 2.02 | 17p13.3 | YWHAE | 266106 |
| 2.71 | 11 | PIG11 | 365972 | 2.02 | 11p11.2–p11.11 | ACP2 | 70332 |
| 2.69 | 11q13 | CCND1 | 841641 | 2.02 | 4 | CCNI | 248295 |
| 2.64 | Unknown | EST | 488574 | 2.01 | 15q25 | NTRK3 | 35356 |
| 2.55 | 8p21 | NEFL | 28422 | 2.00 | 9q34.3 | PTGES | 491213 |
Relative gene expression ratios of neuroblastoma compared to Ewing’s sarcoma.
Map, chromosomal location.
IMAGE, International Molecular Analysis of Genomics and their Expression.