Table 3.

Effect of Fixation

DNA	FFPE	P value
B cell lymphomas	57 /93 (61.3%)	22 /55 (41.8%)	0.012
T cell lymphomas	4 /110 (3.6%)	7 /64 (10.6%)	0.056
Non-reportable results	6 /209 (2.8%)	90 /209 (43.1%)	<0.0001

Data pertain to the 11 paired samples only (5 B cell, 6 T cell, with results obtained from 19 laboratories, thus 11 × 19 = 209 possible results). Fractions and percentages reflect the detection of a monoclonal IgH gene rearrangement. DNA, DNA extracted from fresh or frozen tissue; FFPE, formalin-fixed, paraffin-embedded tissue, DNA extracted in individual laboratories.