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. 2002 May;4(2):81–89. doi: 10.1016/S1525-1578(10)60685-X

Table 5.

Effect of Using Additional FR Primers

FR primer Number of laboratories (%) True positives (%) False positives (%)
FRIII only 8/17 (47%) 55/96 (57.3%)* 6/91 (6.6%)
+ FRII 7/17 (41%) 64/87 (73.6%)* 1/75 (1.3%)
+ FRI 1/17 (6%) 8/11 (72.2%) 2/8 (25%)
Not stated 1/17 (6%) 6/13 (46.2%) 0/10 (0%)
Totals 17/17 (100%) 147/232 (63.4%) 13/208 (6.3%)

Fractions reflect total number of tests positive/total number of tests performed by the participating laboratories, on all distributed material (DNA and paraffin-embedded). True positives, finding a monoclonal IgH gene rearrangement by PCR in B cell lymphomas; False positives, finding a monoclonal IgH gene rearrangement by PCR in T cell lymphomas.

P = 0.021.

P = 0.09.

P = 0.011.