FIG. 1.

Effects of N-acyl-cyclopentylamides on lasB-lacZ expression in P. aeruginosa PAO1 and chemical structures of PAI1, PAI2, and C10-CPA. N-Acyl-pentylamides with acy side chain lengths ranging from C4 to C12 are abbreviated C4-CPA to C12-CPA. PAO1(pβ01) was cultivated for 24 h in the presence of 250 μM N-acyl-cyclopentylamide. Then β-galactosidase activity was determined. Horizontal bars represent the standard deviations of measurements done in four separate experiments. Different letters on the right sides of the bars indicate a significant difference (P < 0.01) among the treatments.