FIG. 6.

(A) Dose response for inhibitory effects of C10-CPA on lasI-lacZ expression in P. aeruginosa PAO1. (B) Inhibition of PAI1 signaling by C10-CPA. The LasI-RhlI signal mutant PAO-MW1 harboring pβ03 was grown in the presence of and in the absence of 10 nM PAI1 and 250 μM C10-CPA for 9 h, and β-galactosidase activity was measured. Vertical bars represent the standard deviations of measurements done in four separate experiments. Different letters above bars indicate a significant difference (P < 0.01) among the treatments.