Skip to main content
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1964 Aug;45(2):209–219.

Ultrastructural Studies of Inh-Induced Neuropathy in Rats

I. Early Axonal Changes

William W Schlaepfer, Hermann Hager
PMCID: PMC1907187  PMID: 14202521

Full text

PDF
210

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BALZER H., HOLTZ P., PALM D. [Studies on the biochemical principles of the convulsive effect of hydrazine]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1960;239:520–552. [PubMed] [Google Scholar]
  2. BIEHL J. P., VILTER R. W. Effect of isoniazid on vitamin B6 metabolism; its possible significance in producing isoniazid neuritis. Proc Soc Exp Biol Med. 1954 Mar;85(3):389–392. doi: 10.3181/00379727-85-20891. [DOI] [PubMed] [Google Scholar]
  3. BOONE I. U., STRANG V. G., ROGERS B. S. Effect of pyridoxal on uptake of C14-activity from labeled isoniazid by Mycobacterium tuberculosis. Am Rev Tuberc. 1957 Oct;76(4):568–578. doi: 10.1164/artpd.1957.76.4.568. [DOI] [PubMed] [Google Scholar]
  4. BOONE I. U., WOODWARD K. T. Relationship of pyridoxine and its derivatives to the mechanism of action of isoniazid. Proc Soc Exp Biol Med. 1953 Nov;84(2):292–296. doi: 10.3181/00379727-84-20621. [DOI] [PubMed] [Google Scholar]
  5. FINEAN J. B., WOOLF A. L. An electron microscope study of degenerative changes in human cutaneous nerve. J Neuropathol Exp Neurol. 1962 Jan;21:105–115. doi: 10.1097/00005072-196201000-00009. [DOI] [PubMed] [Google Scholar]
  6. FISHER E. R., TURANO A. Schwann cells in wallerian degeneration. Arch Pathol. 1963 May;75:517–527. [PubMed] [Google Scholar]
  7. GLIMSTEDT G., WOHLFART G. Electron microscopic observations on Wallerian degeneration in peripheral nerves. Acta Morphol Neerl Scand. 1960;3:135–146. [PubMed] [Google Scholar]
  8. HESS A. The fine structure of degenerating nerve fibers, their sheaths, and their terminations in the central nerve cord of the cockroach (Periplaneta americana). J Biophys Biochem Cytol. 1960 Apr;7:339–344. doi: 10.1083/jcb.7.2.339. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. KLINGHARDT G. W., RADENBACH K. L., MROWKA S. Neurologische Komplikationen bei der Tuberkulosebehandlung mit Isonikotinsäurehydrazid. Wien Med Wochenschr. 1954 Apr 10;104(15):301–306. [PubMed] [Google Scholar]
  10. LEE J. C. Electron microscopy of Wallerian degeneration. J Comp Neurol. 1963 Feb;120:65–79. doi: 10.1002/cne.901200107. [DOI] [PubMed] [Google Scholar]
  11. LEHMANN H. J. [Structure and function of peripheral nerve fibers of warm-blooded animals in the early stage of wallerian degeneration]. Z Zellforsch Mikrosk Anat. 1960;51:283–319. [PubMed] [Google Scholar]
  12. LEVENE C. I. The lathyrogenic effect of isonicotinic acid hydrazide (INAH) on the chick embryo and its reversal by pyridoxal. J Exp Med. 1961 Apr 1;113:795–810. doi: 10.1084/jem.113.4.795. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. MAXFIELD M. Axoplasmic proteins of the squid giant nerve fiber with particular reference to the fibrous protein. J Gen Physiol. 1953 Nov 20;37(2):201–216. doi: 10.1085/jgp.37.2.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. OESTREICHER R., DRESSLER S. H., MIDDLEBROOK G. Peripheral neuritis in tuberculous patients treated with isoniazid. Am Rev Tuberc. 1954 Sep;70(3):504–508. doi: 10.1164/art.1954.70.3.504. [DOI] [PubMed] [Google Scholar]
  15. PALADE G. E. A study of fixation for electron microscopy. J Exp Med. 1952 Mar;95(3):285–298. doi: 10.1084/jem.95.3.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. REVEL J. P., NAPOLITANO L., FAWCETT D. W. Identification of glycogen in electron micrographs of thin tissue sections. J Biophys Biochem Cytol. 1960 Dec;8:575–589. doi: 10.1083/jcb.8.3.575. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. TAXI J. Etude au microscope électronique de la dégénérescence wallérienne des fibres nerveuses amyéliniques. C R Hebd Seances Acad Sci. 1959 May 11;248(19):2796–2798. [PubMed] [Google Scholar]
  18. TERRY R. D., HARKIN J. C. Wallerian degeneration and regeneration of peripheral nerves. Prog Neurobiol. 1959;4:303–320. [PubMed] [Google Scholar]
  19. VIAL J. D. The early changes in the axoplasm during wallerian degeneration. J Biophys Biochem Cytol. 1958 Sep 25;4(5):551–555. doi: 10.1083/jcb.4.5.551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. VILTER R. W., MUELLER J. F., GLAZER H. S., JARROLD T., ABRAHAM J., THOMPSON C., HAWKINS V. R. The effect of vitamin B6 deficiency induced by desoxypyridoxine in human beings. J Lab Clin Med. 1953 Sep;42(3):335–357. [PubMed] [Google Scholar]
  21. WATSON M. L. Staining of tissue sections for electron microscopy with heavy metals. J Biophys Biochem Cytol. 1958 Jul 25;4(4):475–478. doi: 10.1083/jcb.4.4.475. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. WEBSTER H. D., SPIRO D. Phase and electron microscopic studies of experimental demyelination. I. Variations in myelin sheath contour in normal guinea pig sciatic nerve. J Neuropathol Exp Neurol. 1960 Jan;19:42–69. [PubMed] [Google Scholar]
  23. WEBSTER H. D., SPIRO D., WAKSMAN B., ADAMS R. D. Phase and electron microscopic studies of experimental demyelination. II. Schwann cell changes in guinea pig sciatic nerves during experimental diphtheritic neuritis. J Neuropathol Exp Neurol. 1961 Jan;20:5–34. doi: 10.1097/00005072-196101000-00002. [DOI] [PubMed] [Google Scholar]
  24. WEBSTER H. D. Schwann cell alterations in metachromatic leukodystrophy: preliminary phase and electron microscopic observations. J Neuropathol Exp Neurol. 1962 Oct;21:534–554. doi: 10.1097/00005072-196210000-00003. [DOI] [PubMed] [Google Scholar]
  25. WEBSTER H. D. Transient, focal accumulation of axonal mitochondria during the early stages of wallerian degeneration. J Cell Biol. 1962 Feb;12:361–383. doi: 10.1083/jcb.12.2.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. YONEDA M., KATO N., OKAJIMA M. Competitive action of isonicotinic acid hydrazide and vitamin B6 in the formation of indole by E. coli. Nature. 1952 Nov 8;170(4332):803–803. doi: 10.1038/170803a0. [DOI] [PubMed] [Google Scholar]
  27. ZBINDEN G., STUDER A. Experimenteller Beitrag zur Frage der Isoniazid-Neuritis und ihrer Beeinflussung durch Pyridoxin. Z Tuberk. 1955;107(1-3):97–107. [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES