Table 2.
Estimates of Significant Changes in Gene Expression
| Treatment | Global normalization | Z transformation | Genes in common† | |||
|---|---|---|---|---|---|---|
| PMA + 1* | PMA + 28† | PMA + 1* | PMA + 28† | PMA + 1* | PMA + 28† | |
| Genes (no.) up-regulated | 32 | 226 | 22 | 24 | 22 | 24 |
| Genes (no.) down-regulated | 67 | 19 | 20 | 25 | 20 | 20 |
PMA + lonomycin
PMA + anti-CD28
The number of genes up-regulated and down-regulated by treatments shown according to traditional fold ratio or Z ratio. Significance levels for fold change estimates were set at two-fold changes up or down: for Z ratios the significance level was set at ± 2 Z ratio (approximate 95% confidence level).