Table 2.
EBV-Associated Diseases
| Disease | Proportion of cases EBV-related | Reference |
|---|---|---|
| Benign, reactive infections | ||
| Infectious mononucleosis | >99 | 22 |
| Oral hairy leukoplakia | >95 | 8 |
| Inflammatory pseudotumor | 40 | 60 |
| Non-Hodgkin’s lymphomas and immunodeficiency-related neoplasms | ||
| Non-Hodgkin’s lymphoma, all subtypes | 5 | 5 |
| Non-Hodgkin’s lymphoma, AIDS-related | 40 | 61 |
| Brain lymphoma, AIDS-related | 95 | 62 |
| Brain lymphoma, immunocompetent hosts | 5 | 63 |
| Post transplant lymphoproliferative disorder (PTLD) | 95 | 3 |
| Burkitt’s lymphoma, African | >95 | 64 |
| Burkitt’s lymphoma, North American | 20 | 64 |
| Burkitt’s lymphoma, AIDS-related | 30 | 65 |
| Lymphoma, primary immunodeficiency | most | 66 |
| Lymphomatoid granulomatosis (B cell) | most | 67 |
| Peripheral T cell lymphoma | 40 | 28 |
| Nasal T/NK cell lymphoma | >95 | 68 |
| Smooth muscle tumors in AIDS or transplant patients | >95 | 69 |
| Hodgkin’s disease | ||
| Hodgkin’s disease, all subtypes | 40 | 4 |
| Hodgkin’s disease, mixed cellularity | 70 | 4 |
| Hodgkin’s disease, nodular sclerosis | 20 | 4 |
| Hodgkin’s disease, lymphocyte predominant | <5% | 70 |
| Hodgkin’s disease, lymphocyte depleted | 50 | 4 |
| Hodgkin’s disease, AIDS-related | >95 | 71 |
| Carcinomas | ||
| Nasopharyngeal carcinoma, Asian | >95 | 2 |
| Nasopharyngeal carcinoma, North American | 75 | 29 |
| Lymphoepithelioma-like carcinoma, foregut derived | most | 6 |
| Gastric adenocarcinoma | 7 | 7 |