Table 1.
Cytogenetic Findings in Adamantinoma and Osteofibrous Dysplasia
| Diagnosis | Age, Sex | Karyotype | Reference |
|---|---|---|---|
| OFD | ?, M | 46,XY | Tarkkanen et al. 7 |
| OFD | 11, M | 47,XY,+12 | Bridge et al. 5 |
| OFD | 19, M | 49,XY,+7,+8,+22 | Bridge et al. 5 |
| OFD | 18, F | 52,XX,+5,+7,+7,+8,+21,+21 | Bridge et al. 6 |
| Classic adamantinoma | 15, F | 46,XX,t(1;13;22)(q22;q12;p13), t(15;17)(q12;p13) | Mandahl et al. 2 |
| Classic adamantinoma* | 15, M | 52,XY,t(7;13)(q32;q14),+7,+12,+13,+19,+der(7)t(7;13)(q32;q14),+der(13) t(7;13)(q32;q14) | Sozzi et al 3 |
| Classic adamantinoma† | 22, M | 50,XY,+7,+8,+12,+19 | Hazelbag et al. 4 |
| Classic adamantinoma | 10, M | 50,XY,+7,+8,t(10;12)(p10;p10),+12,+19 | Hazelbag et al. 4 |
| Classic adamantinoma | 37, M | 51,XY,+X,+7,+12,+19,+21/50, XY,+X,+7,+12,+21 | Hazelbag et al. 4 |
| Differentiated adamantinoma | 5, M | 47,XY,+mar/48,XY,+7,+8 | Hazelbag et al. 4 |
| Differentiated adamantinoma | 37, F | 46,XX,t(2;11)(p23;q14)inv(11) (p14q14) | Hazelbag et al. 4 |
| Classic adamantinoma | 37, F | 54,XX,−1,+5,+der(7)t(?1;7) (q21;q22),+der(8)t(1;8) (q21;q24.3),+der(9)t(1;9)(p32;q34),+19,+20,+21,+mar1,+mar2 | Present report |
| Differentiated adamantinoma | 20, M | 54,XY,+5,+7,+8,+12,+12,+14,+19,+21/53,XY,+4,+5,+7,+8,+12,+14,−16,+17,−18,+21,+mar | Present report |
| Classic adamantinoma | 16, F | nuc ish 7cen(D7Z1×3),8cen(D8Z1×3),12cen(D12Z1×2),19q12–13.1(F1×3) | Present report |
| Classic adamantinoma | 14, M | nuc ish 7cen(D7Z1×4),8cen(D8Z1×5–8),12cen(D12Z1×4),19q12–13.1(F1×4) | Present report |
OFD, osteofibrous dysplasia.
The t(7;13) in this case was constitutional.
The following abnormal clone was detected in one additional cell: 49,XY,del(1p),+7,+8,+12(inc).