Table 4.
Loci | W/W | W/w | w/w |
---|---|---|---|
TNF-α (−308) | 3/90 (3.3%) | 21/90 (23.3%) | 66/90 (73.3%) |
TNF-α (−238) | 83/90 (92.2%) | 7/90 (7.8%) | 0/90 (0.0%)† |
TNF-β (+250) | 37/90 (41.1%) | 44/90 (48.9%) | 9/90 (10%) |
IL-1 (−3953) | 5/90 (5.5%) | 42/90 (46.7%) | 43/90 (47.8%) |
IL-6 (−174) | 37/90 (41.1%) | 43/90 (47.8%) | 10/90 (11.1%) |
IL-10 (−592) | 4/90 (4.4%) | 35/90 (38.9%) | 51/90 (56.7%) |
PAI-1 (−675) | 20/90 (22.2%) | 57/90 (63.3%) | 14/90 (15.5%) |
TLR4299 | 83/90 (92.2%) | 7/90 (7.8%) | 0/90 (0%)† |
W denotes the more frequent genotype, w denotes the variant genotype (SNP).
Given their infrequent nature, w/w genotypes for TNF-α (−238) and TLR4 299 were not observed.