Table 4.
Accumulations of Genetic Alterations in Colorectal Tumors Based on a Modified Vienna Classification
| Accumulation | Category 3 (%) | Category 4 (%) | Category 5 (%) | Advanced cancer (%) |
|---|---|---|---|---|
| Total | 86 | 42 | 15 | 45 |
| 0 | 44 (51.2) | 9 (21.4) | 1 (6.7) | 2 (4.4) |
| 1 | 32 (37.2) | 15 (35.7) | 2 (13.3) | 3 (6.7) |
| 2 | 7 (8.1) | 10 (23.8) | 5 (33.3) | 4 (8.9) |
| 3 | 3 (3.5) | 5 (11.9) | 4 (26.7) | 6 (13.3) |
| 4 | 0 | 2 (4.8) | 2 (13.3) | 14 (31.1) |
| 5 | 0 | 0 | 1 (6.7) | 8 (17.7) |
| 6 | 0 | 0 | 0 | 5 (11.1) |
| 7 | 0 | 0 | 0 | 3 (6.7) |
| 8 | 0 | 0 | 0 | 0 |
Genetic alterations examined: allelic loss, 17p; 5q; 18q; 1p; 8p; 22p; mutation, p53; Ki-ras.