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SX-007 increases SMA-560–specific CD8+ T-cell degranulation. (A) Representative histograms of surface CD107a staining on CD8+ T-cells (CD8α+CD3ɛ+) from lymph nodes. (B) Scatter plots of percentage of tumor-specific CD8+ T-cells that mobilize CD107a to the surface. The percentage of cells that spontaneously mobilize CD107a (in the absence of SMA-560 cells) was subtracted to calculate tumor-specific activity.
