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Analysis of nucleosome spacing. Chromatin was reconstituted at the indicated KCl concentrations from control or acetylated histones and digested with MNase to reveal the NRL. As the KCl concentration is raised the NRL increases to a similar extent for both types of chromatin. Dots marking the position of the tetranucleosomal fragments. A negative print of the ethidium-stained DNA is shown.
