Abstract
A high incidence of pancreatic neoplasms was induced in Syrian golden hamsters following subcutaneous applications of diisopropanolnitrosamine (DIPN) once weekly for life. The tumor latency was as short as 15 weeks. In clinical and morphologic aspects the induced pancreatic tumors closely resembled those of humans.
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- CAMPBELL J. A., CRUICKSHANK A. H. Cystadenoma and cystadenocarcinoma of the pancreas. J Clin Pathol. 1962 Sep;15:432–437. doi: 10.1136/jcp.15.5.432. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CORNES J. S., AZZOPARDI J. G. Papillary cystadenocarcinoma of the pancreas with report of two cases. Br J Surg. 1959 Sep;47:139–144. doi: 10.1002/bjs.18004720204. [DOI] [PubMed] [Google Scholar]
- Druckrey H., Ivankovic S., Bücheler J., Preussmann R., Thomas C. Erzeugung von Magen- und Pankreas-Krebs beim Meerschweinchen durch Methylnitroso-harnstoff und -urethan. Z Krebsforsch. 1968;71(2):167–182. [PubMed] [Google Scholar]
- GLENNER G. G., MALLORY G. K. The cystadenoma and related nonfunctional tumors of the pancreas; pathogenesis, classification, and significance. Cancer. 1956 Sep-Oct;9(5):980–996. doi: 10.1002/1097-0142(195609/10)9:5<980::aid-cncr2820090519>3.0.co;2-s. [DOI] [PubMed] [Google Scholar]
- Hayashi Y., Hasegawa T. Experimental pancreatic tumor in rats after intravenous injection of 4-hydroxyaminoquinoline 1-oxide. Gan. 1971 Aug;62(4):329–330. [PubMed] [Google Scholar]
- LEACH W. B. Carcinoma of the pancreas; a clinical and pathologic analysis of 39 autopsied cases. Am J Pathol. 1950 Mar;26(2):333–347. [PMC free article] [PubMed] [Google Scholar]
- Levin D. L., Connelly R. R. Cancer of the pancreas. Available epidemiologic information and its implications. Cancer. 1973 May;31(5):1231–1236. doi: 10.1002/1097-0142(197305)31:5<1231::aid-cncr2820310529>3.0.co;2-c. [DOI] [PubMed] [Google Scholar]
- MILLER J. R., BAGGENSTOSS A. H., COMFORT M. W. Carcinoma of the pancreas; effect of histological types and grade of malignancy on its behavior. Cancer. 1951 Mar;4(2):233–241. doi: 10.1002/1097-0142(195103)4:2<233::aid-cncr2820040205>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
- SOMMERS S. C., MEISSNER W. A. Unusual carcinomas of the pancreas. AMA Arch Pathol. 1954 Aug;58(2):101–111. [PubMed] [Google Scholar]
- Wynder E. L., Mabuchi K., Maruchi N., Fortner J. G. Epidemiology of cancer of the pancreas. J Natl Cancer Inst. 1973 Mar;50(3):645–667. doi: 10.1093/jnci/50.3.645. [DOI] [PubMed] [Google Scholar]