Table 1.
Kinetic constants used in the computer model
| Reaction | Kon M s−1 | Koff s−1 | Reference |
|---|---|---|---|
| Impβ+NUP | 1.00E+08 | 10 | Ben-Efraim and Gerace (2001) |
| NTF2+NUP | 1.00E+07 | 200 | Chaillan-Huntington et al (2000) |
| Cas+NUP | 1.00E+07 | 200 | Estimate from Chaillan-Huntington et al (2000) |
| CRM1+NUP | 1.00E+07 | 200 | Estimate from Chaillan-Huntington et al (2000) |
| RanGTP+RanBP3 | 1.00E+07 | 10 | Englmeier et al (2001) |
| CRM1+RanBP3 | 1.00E+07 | 1 | Englmeier et al (2001) |
| CRM1−RanBP3+NES | 1.00E+07 | 1 | Lindsay (2001) |
| CRM1−RanBP3+Rt | 1.00E+07 | 1 | Englmeier et al (2001) |
| Crm1−RanBP3−NES+RanGTP | 1.00E+07 | 0.3 | Englmeier et al (2001) |
| CRM1−RanBP3−RanGTP+NES | 1.00E+07 | 0.3 | Lindsay (2001) |
| CRM1−RanBP3−NES−RanGTP+RanBP1 | 3.00E+06 | 4.00E-10 | Estimate from Askjaer et al (1999) |