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O6-alkylguanine elimination from bulk DNA and from the transcribed H-ras gene of the mammary gland after exposure to MeNU or EtNU in vivo, and effect of MGMT inhibition by O6-BeGua. DNA was analyzed for O6-MeGua or O6-EtGua by ISB or immunoaffinity/quantitative PCR. See Results for O6-BeGua exposure conditions. Values are means of duplicate analyses from two (O6-MeGua) or four animals (O6-EtGua) per time point.
