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. 2007 Jul 6;3(7):e126. doi: 10.1371/journal.pcbi.0030126

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© 2007 Yao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Sequence alignment of a conserved RNA structure found in the 5′ UTR of Firmicute rplM–rpsI operons. The examples shown are representative of 27 total sequences in the complete alignment, available in the online supplement at http://bio.cs.washington.edu/supplements/yzizhen/pipeline. Details are as in the legend for Figure 3 with additional species abbreviations:

Lde, Lactobacillus delbruecki; Lla, Lactococcus lactis; Lme, Leuconostoc mesenteroides; Ppe, Pediococcus pentosaceus; Sag, Streptococcus agalactiae; Sep, Staphylococcus epidermidis; Sha, Staphylococcus haemolyticus; Ssa, Staphylococcus saprophyticus.

(B) Consensus sequence and secondary structure.

(C) Structural model of the B. subtilis L13–S9 mRNA leader, showing a possible alternate structure that could be stabilized by L13 or S9 binding to repress translation.