Skip to main content
. Author manuscript; available in PMC: 2008 Feb 1.
Published in final edited form as: Bone. 2006 Oct 24;40(2):345–353. doi: 10.1016/j.bone.2006.09.011

Figure 3. CML-collagen inducedCollagen stimulates apoptosis is mediated through RAGE.

Figure 3

Primary cultures of human adult osteoblastic cells were incubated with CML-collagen (200μg/ml) in presence or absence of antibody specific for the extra-cellular domain of RAGE (10 μg/ul) or non-immune serum (10 μg/ul) for 24 hours. In some cases cells were incubated with antiserum or non-immune serum alone. The extent of apoptosis was determined by ELISA. Each value represents the mean of 4 replicates ± SEM. The experiment was performed three times with similar results.