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. Author manuscript; available in PMC: 2007 Jul 9.
Published in final edited form as: J Comp Neurol. 2005 Mar 21;483(4):458–475. doi: 10.1002/cne.20437

Fig. 11.

Fig. 11

Schematic representation of calretinin immunostaining in the young adult ferret cochlear nucleus and IC following cochlear ablation at hearing onset. In control animals (A), multipolar neurons (stars) in anterior ventral cochlear nucleus and posterior ventral cochlear nucleus project bilaterally although calretinin immunostained neurons project predominantly to the ipsilateral IC. In cochlear ablation (B), upregulation of calretinin in multipolar cells in the intact cochlear nuclei contributes to increased immunostaining in the calretinin plexus in the IC on the side contralateral to the ablation. Conversely, downregulation of calretinin in multipolar cells in the deprived cochlear nucleus contributes to reduce immunostaining plexus of the IC on the side ipsilateral to the ablation. Dashed lines represent deprived projections while solid lines intact projections. Calretinin immunostained cells are indicated with solid stars and calretinin immunonegative cells with open stars. Different gray colors indicate different levels of immunostained neuropil or fibers in each nucleus. Accordingly, darker gray color indicates an upregulation and lighter gray color a downregulation in calretinin immunostaining. AVCN, anterior ventral cochlear nucleus; DCN, dorsal cochlear nucleus; IC, inferior colliculus; PVCN, posterior ventral cochlear nucleus.