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. 2007 Apr 30;51(7):2293–2303. doi: 10.1128/AAC.00289-07

FIG. 4.

FIG. 4.

Synthesis of 1-methyl-3-(trifluoromethyl)-N-[4-(pyrrolidinylsulfonyl)-phenyl]-1H-pyrazole-5-carboxamide (16677). Reagents: (a) MeOH, reflux; (b) n-BuLi/i-Pr2NH, then CO2; (c) (COCl)2, dimethylformamide(cat.), CH2Cl2, 0°C-rt; (d) py, CH2Cl2, rt.