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Effects of ΔG11024 on WNV resistance to the 3′ CSI PPMO. (A) Resistance profiles of R-3′ CSI virus from selection II and four recombinant viruses (G8074A, G10965U, ΔG11024, and G8074A G10965U viruses). See Materials and Methods for details. (B) Effects of ΔG11024 on the MFold-predicted 3′ stem-loop structure of the WNV genome. Structural changes caused by ΔG11024 are highlighted in gray.
