TABLE 2.
Vancomycin MIC versus eradication rates
| Vancomycin MIC (μg/ml) | No. of isolates | Median DTEa | Median duration of vancomycin therapy (days) | Eradication rate by EOTb | Median reduction in log10 CFU/ml |
|---|---|---|---|---|---|
| 0.5 | 13 | 6.0 | 13.0 | 10/13 (77) | 3.06 |
| 1.0 | 7 | 9.5 | 17.0 | 5/7 (71) | 3.09 |
| 2.0 | 14 | >15.0c | 18.5 | 3/14 (21) | 2.75 |
a
DTE, day to eradication.
b
EOT, end of treatment. The eradication rate data represent the number of patients from the organism was eradicated/total number of patients in the group (percent).
c
The median time to eradication is greater than 15 days, as only 21% of patients showed clearance of bacteremia.