TABLE 2.
Change in expression levels of mycobacterial genes with similar expression patterns in samples collected from mice relative to 7H9 broth
| Gene | Product | Annotationa | Change (n-fold) ± SD at (days):
|
||
|---|---|---|---|---|---|
| 28 | 45 | 60 | |||
| rv0156 | PntAB | Nicotinamide nucleotide transhydrogen subunit | 2.72 ± 0.27 | 1.87 ± 0.22 | 1.57 ± 0.31 |
| rv0348 | Rv0348 | Possible transcriptional regulator, TetR/AcrR family | 1.59 ± 0.25 | 1.49 ± 0.11 | 1.67 ± 0.36 |
| rv0981 | MprA | Two-component response regulator | 4.83 ± 2.25 | 2.26 ± 0.39 | 9.51 ± 5.17 |
| rv1062 | Rv1062 | Unknown conserved protein | 3.67 ± 0.2 | 2.77 ± 0.15 | 1.99 ± 0.31 |
| rv2080 | LppJ | Possible lipoprotein | 3.43 ± 0.33 | 2.74 ± 0.22 | 2.13 ± 0.37 |
| rv2326c | Rv2326c | Putative ABC transporter | 3.36 ± 0.26 | 2.95 ± 0.19 | 2.67 ± 0.56 |
| rv3079c | Rv3079c | Unknown conserved protein | −2.51 ± 0.57 | −2.58 ± 0.6 | −3.24 ± 1.19 |
| rv3103c | Rv3103c | Proline-rich proteins of unknown function | −3.15 ± 0.96 | −3.42 ± 0.96 | −3.08 ± 0.8 |
| rv3685c | Rv3685c | Probable cytochrome P-450 | −2.3 ± 0.55 | −2.17 ± 0.4 | −2.98 ± 0.84 |
| rv3799c | AccD4 | Probable propionyl-coenzyme A carboxylase | −3.49 ± 0.49 | −2.96 ± 0.4 | −3.58 ± 1.07 |
| rv3830c | Rv3830c | Transcriptional regulator protein | −1.87 ± 0.38 | −1.92 ± 0.42 | −1.74 ± 0.29 |
| rv3871 | Rv3871 | Unknown conserved protein | −2.6 ± 0.48 | −2.44 ± 0.58 | −2.85 ± 0.71 |
Tuberculist website (http://genolist.pasteur.fr/TubercuList/).