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. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Int Immunopharmacol. 2006 Nov 20;7(3):277–286. doi: 10.1016/j.intimp.2006.10.006

Fig 6.

Fig 6

Effect of tyrosine kinase inhibitor on the histamine mediated phosphorylation of STAT6. C57BL/6 splenocytes were treated with tyrosine kinase inhibitor tyrphostin (10−6 M) for 30 min followed by treatment with or without histamine (10−11 M) for 1 h. The cells were further stimulated with the PMA + ionomycin (10 ng/ml and 1 ug/ml, respectively) for 6h and subsequently lysed. The levels of phosphorylated STAT6 were detected by Western Blot Analysis. Lane: untreated; lane 2: PMA + ionomycin; lane 3: PMA + ionomycin + histamine 10−11 M; lane 4: PMA + ionomycin + histamine 10−11 M + tyrphostin 10−6 M; lane 5: PMA + ionomycin + tyrphostin 10−6 M.