Table 4.
Erythromycina |
Tetracyclinea |
Vancomycina |
|||||||
---|---|---|---|---|---|---|---|---|---|
Enterococcus spp. source | MIC50 | MIC90 | MIC range | MIC50 | MIC90 | MIC range | MIC50 | MIC90 | MIC range |
Up-gradient groundwater (n = 30) | 16 | 60.8 | 1–128 | < 1 | < 1 | < 1–32 | 0.25 | 58 | 0.25–> 64 |
Down-gradient groundwater (n = 26) | 2 | > 256 | < 0.5–> 256 | 2 | 64 | < 1–> 256 | 4 | 8 | 0.25–8 |
Up-gradient surface water (n = 22) | 1 | 2 | < 0.5–4 | < 1 | 108.8 | < 1–128 | 2 | 8 | 0.5–8 |
Down-gradient surface water (n = 107) | 2 | > 256 | < 0.5–> 256 | 2 | 153.6 | < 1–> 256 | 2 | 8 | 0.25–> 64 |
Manure pit (n = 15) | > 256 | > 256 | < 0.5–> 256 | 128 | 179.2 | < 1–> 256 | 0.5 | 2 | 0.5–2 |
MIC50, MIC required to inhibit the growth of 50% of organisms.
CLSI resistance breakpoints are as follows: erythromycin, ≥ 8 μg/mL; tetracycline, ≥ 16 μg/mL; vancomycin, ≥ 32 μg/mL (CLSI 2002).