Figure 8.

Identification of unique EE and TAM differentially expressed genes. Treatment specific differentially expressed genes were identified by excluding a list obtained using a more relaxed criteria (P1(t) > 0.9; |fold change| ≥ 1.4) for one treatment from the differentially expressed genes identified using the standard criteria (P1(t) > 0.999; |fold change| ≥ 1.5) of the second treatment to identify gene expression changes that were more likely to be unique to one treatment. (A) A liberal list of TAM-induced genes identified, using a relaxed criteria of P1(t) ≥ 0.9 and |fold change| ≥ ± 1.4, was excluded from the EE differentially expressed gene list using the standard selection criteria of P1(t) ≥ 0.999 and |fold change| ≥ ± 1.5 to identify 240 genes more likely to be differentially expressed by EE alone. (B) Using a similar approach, a list of 60 genes more likely to be differentially expressed by TAM alone was generated. Lists of EE and TAM specific genes are provided in Additional files 4 and 5.