TABLE 1.

Parameters for SOS signaling, NER, TLS, and RR

Parameter	Description	Value (s−1)
krep	DNA replication	900
kreca_on	RecA binding onto ssDNA	0.003
kreca_off	RecA unbind from ssDNA	2 (55)
kclexa	RecA catalyzed LexA cleavage	7.5 × 10−6
krecu	RecA catalyzed UmuD cleavage	1 × 10−5
kner	NER	1.5 × 10−6
ktls	TLS	4 × 10−6
ThrTLS	RecA* threshold for TLS	50
krrDSG	RR on DSG	0.05
krrRF	RR on replication fork	0.0001
ThrRR	RecA* threshold for RR	480
kslow_on	UmuD2 binding onto Pol III	0.025
kslow_off	UmuD2 unbinding from Pol III	10
rslow	Replication rate fold change	3
kDD1	UmuD binding	0.001
kDD2	UmuD2 unbinding	0.0058
kD′D′1	UmuD′ binding	0.001
kD′D′2	UmuD′2 unbinding	0.0058
kDD′1	UmuD and UmuD′ binding	0.0058
kDD′2	UmuDD′ unbinding	0.0029
kD′C1	UmuD′2 and UmuC binding	0.001
kD′C2	UmuD′2C unbinding	0.24
kDDdp	UmuD2 degradation	0.0017
kD′dp	UmuD′ degradation	0.00064
kD′D′dp	UmuD′2 degradation	0.00064 (40)
kDD′dp	UmuDD′ degradation	0.00064
kD′Cdp	UmuD′2C degradation	0.0019
kClp	UmuDD′ degraded by ClpXP	0.001