. 2007 Feb 7;454(2):321–334. doi: 10.1007/s00424-007-0210-x

Table 3.

Functional parameters of isolated perfused rat kidneys in control rats (no additional treatment) and after exposure to LPS⁻ or LPS⁺ for 12 h

Parameter	Controls (n = 4)	LPS⁻ (n = 4)	LPS⁺ (n = 6)
GFR (μl/min)	350 ± 25	380 ± 17	290 ± 20^a
Diuresis (μl/min)	18.6 ± 1.8	21.1 ± 1.3	17.4 ± 1.0
FR_water (%)	94.7 ± 0.2	94.5 ± 0.3	92.7 ± 0.6^a
RPP (mmHg)^b	88.4 ± 1.5	84.5 ± 1.7	88.7 ± 1.0

Data are expressed as mean ± SE of four to six perfused kidney experiments over the period 25-115 min. Untreated rats served as controls for this model. Kidneys were perfused for 150 min as described in the “Materials and methods” section

^aSignificantly different from perfused control kidney (P < 0.05)

^bConstant flow during the experiments was 18 ± 0.5 ml/min

FR fractional reabsorption, RPP renal perfusion pressure