Skip to main content
PMC home page
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1966 Jul;49(1):113–128.

Early hepatic parenchymal changes induced in the rat by aflatoxin B1.

W H Butler
PMCID: PMC1916467  PMID: 5944755

Full text

PDF
117

Images in this article

121Figs 1-3
on p.121
123Figs 4-5
on p.123
124Fig 6
on p.124
125Fig 7
on p.125
127Figs 8-9
on p.127
128Fig 10
on p.128

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BASSI M. Electron microscopy of rat liver after carbon tetrachloride poisoning. Exp Cell Res. 1960 Aug;20:313–323. doi: 10.1016/0014-4827(60)90160-9. [DOI] [PubMed] [Google Scholar]
  2. BUTLER W. H. ACUTE TOXICITY OF AFLATOXIN B-1 IN RATS. Br J Cancer. 1964 Dec;18:756–762. doi: 10.1038/bjc.1964.87. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bruni C., Porter K. R. The Fine Structure of the Parenchymal Cell of the Normal Rat Liver: I. General Observations. Am J Pathol. 1965 May;46(5):691–755. [PMC free article] [PubMed] [Google Scholar]
  4. Butler W. H., Clifford J. I. Extraction of aflatoxin from rat liver. Nature. 1965 Jun 5;206(988):1045–1046. doi: 10.1038/2061045a0. [DOI] [PubMed] [Google Scholar]
  5. Clifford J. I., Rees K. R. Aflatoxin: a site of action in the rat liver cell. Nature. 1966 Jan 15;209(5020):312–313. doi: 10.1038/209312a0. [DOI] [PubMed] [Google Scholar]
  6. EMMELOT P., BENEDETTI E. L. Changes in the fine structure of rat liver cells brought about by dimethylnitrosamine. J Biophys Biochem Cytol. 1960 Apr;7:393–396. doi: 10.1083/jcb.7.2.393. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FAWCETT D. W. Observations on the cytology and electron microscopy of hepatic cells. J Natl Cancer Inst. 1955 Apr;15(5 Suppl):1475–1503. [PubMed] [Google Scholar]
  8. GUSTAFSSON R. G., AFZELIUS B. A. Comparative effects on rat liver cells after dimethylnitrosamine, 2-fluorenamine, or prednisolone treatment studied by electron microscopy. J Natl Cancer Inst. 1963 May;30:1045–1075. [PubMed] [Google Scholar]
  9. HERDSON P. B., GARVIN P. J., JENNINGS R. B. FINE STRUCTURAL CHANGES PRODUCED IN RAT LIVER BY PARTIAL STARVATION. Am J Pathol. 1964 Aug;45:157–181. [PMC free article] [PubMed] [Google Scholar]
  10. LAPIS K., BERNHARD W. THE EFFECT OF MITOMYCIN-C ON THE NUCLEOLAR FINE STRUCTURE OF KB CELLS IN CELL CULTURE. Cancer Res. 1965 Jun;25:628–645. [PubMed] [Google Scholar]
  11. LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Lafarge C., Frayssinet C., de Recondo A. M. Inhibition par l'aflatoxine de la synthèse de RNA hépatique chez le rat. Bull Soc Chim Biol (Paris) 1965;47(8):1724–1725. [PubMed] [Google Scholar]
  13. MILLONIG G. A modified procedure for lead staining of thin sections. J Biophys Biochem Cytol. 1961 Dec;11:736–739. doi: 10.1083/jcb.11.3.736. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. PALADE G. E. A study of fixation for electron microscopy. J Exp Med. 1952 Mar;95(3):285–298. doi: 10.1084/jem.95.3.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PALADE G. E., SIEKEVITZ P. Liver microsomes; an integrated morphological and biochemical study. J Biophys Biochem Cytol. 1956 Mar 25;2(2):171–200. doi: 10.1083/jcb.2.2.171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. REICH E. BIOCHEMISTRY OF ACTINOMYCINS. Cancer Res. 1963 Sep;23:1428–1441. [PubMed] [Google Scholar]
  17. REYNOLDS R. C., MONTGOMERY P. O., HUGHES B. NUCLEOLAR "CAPS" PRODUCED BY ACTINOMYCIN D. Cancer Res. 1964 Aug;24:1269–1277. [PubMed] [Google Scholar]
  18. SIEKEVITZ P., PALADE G. E. A cytochemical study on the pancreas of the guinea pig. 6. Release of enzymes and ribonucleic acid from ribonucleoprotein particles. J Biophys Biochem Cytol. 1960 Jul;7:631–644. doi: 10.1083/jcb.7.4.631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. SMUCKLER E. A., ISERI O. A., BENDITT E. P. An intracellular defect in protein synthesis induced by carbon tetrachloride. J Exp Med. 1962 Jul 1;116:55–72. doi: 10.1084/jem.116.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Smuckler E. A., Benditt E. P. The early effects of actinomycin on rat liver. Changes in ribosomes and polysomes. Lab Invest. 1965 Oct;14(10):1699–1709. [PubMed] [Google Scholar]
  21. TROTTER N. L. A FINE STRUCTURE STUDY OF LIPID IN MOUSE LIVER REGENERATING AFTER PARTIAL HEPATECTOMY. J Cell Biol. 1964 May;21:233–244. doi: 10.1083/jcb.21.2.233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. TRUMP B. F., SMUCKLER E. A., BENDITT E. P. A method for staining epoxy sections for light microscopy. J Ultrastruct Res. 1961 Aug;5:343–348. doi: 10.1016/s0022-5320(61)80011-7. [DOI] [PubMed] [Google Scholar]
  23. WATSON M. L. Staining of tissue sections for electron microscopy with heavy metals. J Biophys Biochem Cytol. 1958 Jul 25;4(4):475–478. doi: 10.1083/jcb.4.4.475. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES