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. 1998 Feb 17;95(4):1725–1729. doi: 10.1073/pnas.95.4.1725

Figure 4.

Figure 4

Effect of neutralizing antibodies to RANTES, MIP-1α, and MIP-1β on the ability of HIV to infect macrophages. Macrophages were isolated from PBMC from two HIV-seronegative donors (A and B) and allowed to differentiate for 7 days. They then were infected with HIV-1SF162 and maintained in serum-free (Mφ) medium in the absence or presence of an antibody mixture containing 100 μg/ml of anti-RANTES, 50 μg/ml of anti-MIP-1α, and 100 μg/ml of anti-MIP-1β polyclonal goat neutralizing antibodies (Ab). Cell-free culture fluids were collected every 3 days and monitored for particle-associated RT activity. The data are representative of two experiments and were obtained during peak RT activity in the control group.